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Cell Bank and Virus Seed Stock Manufacturing and Storage

Fully characterized Cell Banks and Viral Seed Stocks are essential for successful GMP compliant production. The manufacturing of a uniform Cell Bank is the first step in the production of quality biologics for clinical studies or for commercial use. As a premium One-Stop-Shop Bio-CDMO, Biovian provides the preparation of Cell Banks and Virus Seed Stocks as well as storage in accordance with current regulatory guidelines.


Biovian offers Cell Bank manufacturing and storage for:

  • Research Cell Bank (RCB)
  • Master Cell Bank (MCB)
  • Working Cell Bank (WCB)

Biovian offers Virus Seed Stock manufacturing and storage for:

  • Research Virus Seed Stock (RVSS)
  • Master Virus Seed Stock (MVSS)
  • Working Virus Seed Stock (WVSS)

Cell Bank Manufacturing

Biovian provides microbial, mammalian and insect cell GMP cell bank manufacturing according to current regulatory guidelines. Master Cell Banks, MCBs, are prepared using RCBs as starting material. Working Cell Banks, WCBs, are prepared from the MCBs under defined cell culture conditions and are used for the production of innovative biopharmaceuticals or gene therapy applications. We provide your valuable project with our extensive experience with several adherent and suspension cell lines e.g. E.coli, HEK293, CHO, A549, Vero, CAP, and Sf9. Biovian has dedicated, environmentally controlled manufacturing facilities for both mammalian and microbial cells. Our EMA certified and FDA inspected facilities, including all storage equipment, are continuously monitored and equipped with alarm systems.

Our Cell Bank services cover the following:

  • Generation of RCB
  • GMP-compliant MCB and WCB manufacturing
  • Dedicated clean rooms for the preparation of mammalian and microbial Cell Banks
  • Programmed and controlled freezing of cells
  • GMP-compliant storage of MCB and WCB in a liquid nitrogen vapour phase storage system or in Ultra-Low Temperature Freezer
  • 24/7 monitoring of facilities
  • Flexible shipments to other sites
  • Full characterization service of Cell Banks, conforming with major compendia and regulatory guidelines

Virus Seed Manufacturing and Storage

Biovian provides research Virus Seed stock (RVSS) preparation from plasmid to virus. The manufacturing and storage, under GMP conditions, of high-quality master and working virus seed stock (MVSS/WVSS) provides robust starting materials for Viral Vector and Vaccine projects. Virus Seed manufacturing and banking are performed in dedicated clean rooms ensuring that there is no cross-contamination. We have full capabilities for the preparation of adenovirus and other BSL2 class Virus Seed stocks to support you in your gene therapy, immuno-oncology or vaccine projects.

Our Virus Seed services cover the following:

  • Generation of RVSS
  • GMP MVSS and WVSS manufacture (BSL2)
  • Dedicated clean rooms for viral and non-viral bank preparation.
  • GMP storage of MVSS and WVSS in Ultra-Low Temperature Freezer
  • 24/7 monitoring of facilities
  • Flexible shipments to other sites
  • Full characterization service of Virus Seed conforming with major compendia and regulatory guidelines
Aseptic Fill and Finish
Next step

Aseptic Fill and Finish Service

Biovian provides aseptic Fill and Finish, which is the final, critical step in the GMP manufacturing of biopharmaceutical products. Aseptic Fill and Finish is a core competence of Biovian, with an expertise with continuous operation for over a decade.

Contact Us

Antti Nieminen
Director, Business Development and Projects
Magnus Gustafsson_Biovian
Magnus Gustafsson
Head, Global Business Development
Eero Mustalahti
Manager, Sales and Business Development